Endometrial Immune Dysfunction in Recurrent Pregnancy Loss
نویسندگان
چکیده
منابع مشابه
Endometrial Granulated Lymphocytes in Women Suffering Spontaneous Early Pregnancy Loss
Spontaneous abortion is the most common complication of pregnancy. Several lines of evidence indicate that immunologic effector cells may play a role in the pathogenesis of idiopathic repetitive abortions. Leukocytes form a substantial proportion of stromal cells in decidua and the endometrial granulated lymphocytes (eGL) is the predominant decidual leukocyte population in the first trimester o...
متن کاملMolecular Mechanisms of Recurrent Pregnancy Loss
Introduction: Pregnancy and health is the process in which the egg is fertilized and being able to survive. When pregnancy occurs under some conditions and the fetus is being at risk, it will lead to abortion that occurs involuntarily and spontaneously. Abortions that occur more than two or three times are called recurrent pregnancy loss (RPL). Various etiological factors involved in RPL, inclu...
متن کاملEndometrial beta3 Integrin profile reflects endometrial receptivity defects in women with unexplained recurrent pregnancy loss
BACKGROUND The pathophysiology of recurrent pregnancy loss (RPL) is still unknown in 50% of the cases. Herein we measure the expression of beta3 integrin subunit, a well-known implantation marker, in women with or without RPL and correlate it with the histological dating of the endometrial tissue. METHODS LH-timed endometrial biopsies were obtained from cases (RPL; n = 21, age 33.9+/-4.7) and...
متن کاملI-24: New Molecular Aspects in Recurrent Pregnancy Loss
Background Recurrent pregnancy loss (RPL) is usually defined as three or more consecutive pregnancy losses before 20th gestational week. Many etiological factors have been considered as cause of RPL including genetic factors, uterine anatomical defects, endocrine abnormalities, thrombotic and immunologic factors. Nevertheless, the cause of RPL remains unknown in around half of the patients desp...
متن کاملRecurrent pregnancy loss
Recurrent pregnancy loss (RPL) refers to the consecutive loss of three or more clinically recognized pregnancies prior to the 20th week of gestation (excluding ectopic, molar and biochemical pregnancies). RPL is classified into two categories: primary RPL, which consists of repeated miscarriages in which a pregnancy has never been carried to viability; and secondary RPL, in which a live birth h...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2019
ISSN: 1422-0067
DOI: 10.3390/ijms20215332